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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP1 All Species: 24.24
Human Site: S563 Identified Species: 48.48
UniProt: O94782 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94782 NP_001017415.1 785 88207 S563 L L T P L K L S L E E W S T K
Chimpanzee Pan troglodytes XP_513450 785 88166 S563 L L T P L K L S L E E W S T K
Rhesus Macaque Macaca mulatta XP_001085195 784 88189 S562 L L T P L K L S L E E W S T K
Dog Lupus familis XP_865460 785 88368 S563 L L T P L K L S L E E W S T K
Cat Felis silvestris
Mouse Mus musculus Q8BJQ2 784 87438 S562 L L T P L K L S L E E W S T K
Rat Rattus norvegicus Q569C3 784 87311 S563 L L T P L K L S L E E W S T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026461 794 88314 L574 L T P L K L S L E E W S T K P
Frog Xenopus laevis Q52KZ6 370 42846 V172 S A P D P T W V H E I F Q G T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera NP_001128140 646 73202 R448 V C F P S L P R L L I L Q L K
Nematode Worm Caenorhab. elegans P34547 426 48259 S228 D E D F L D L S I D V E Q N T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001146737 368 41784 V170 K E P P V T L V H K S F Q G I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LAM0 365 41828 V167 K E P I V T W V H K I F Q G I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 94.3 N.A. 88.5 88.6 N.A. N.A. 73.1 20.5 N.A. N.A. N.A. 21.7 22.5 N.A.
Protein Similarity: 100 100 98.5 96.5 N.A. 93.2 92.6 N.A. N.A. 82.4 32.8 N.A. N.A. N.A. 38.8 36.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 6.6 N.A. N.A. N.A. 20 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 20 13.3 N.A. N.A. N.A. 26.6 33.3 N.A.
Percent
Protein Identity: N.A. 21.4 N.A. 20.3 N.A. N.A.
Protein Similarity: N.A. 31.5 N.A. 30.4 N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 9 0 9 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 25 0 0 0 0 0 0 9 67 50 9 0 0 0 % E
% Phe: 0 0 9 9 0 0 0 0 0 0 0 25 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % G
% His: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 9 0 25 0 0 0 17 % I
% Lys: 17 0 0 0 9 50 0 0 0 17 0 0 0 9 59 % K
% Leu: 59 50 0 9 59 17 67 9 59 9 0 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 34 67 9 0 9 0 0 0 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 42 0 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 0 9 0 9 59 0 0 9 9 50 0 0 % S
% Thr: 0 9 50 0 0 25 0 0 0 0 0 0 9 50 17 % T
% Val: 9 0 0 0 17 0 0 25 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 17 0 0 0 9 50 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _